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Dengue Virus I/II/III/IV Nucleic Acid

https://genomika.id/web/image/product.template/109/image_1920?unique=d8b07e1

Short Description: This kit is used for qualitative typing detection of denguevirus (DENV) nucleic acid in suspected patient’s serum sample to help diagnose patients with Dengue fever.


 



                            

                                
                                

                                    

        

            

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		Product name
	
	
	
	

			
	
	
	
		
	
HWTS-FE034-Dengue Virus I/II/III/IV Nucleic Acid Detection Kit (Fluorescence PCR)

 HWTS-FE004-Freeze-dried Dengue Virus I/II/III/IV Nucleic Acid Detection Kit (Fluorescence PCR)

	
	
	
		
	
	
				
		
			
	
	
	
		

		Certificate
	
	
	
	

			
	
	
	
		
	
CE

	
	
	
		
	
	
				
		
			
	
	
	
		

		Epidemiology
	
	
	
	

			
	
	
	
		
	
Dengue fever (DF), which is induced
 by denguevirus (DENV) infection, is one of the most epidemic arbovirus 
infectious diseases. DENV belongs to flavivirus under flaviviridae, and 
can be classified into 4 serotypes according to surface antigen. Its 
transmission medium includes Aedes aegypti and Aedes albopictus, 
prevalent mainly in tropical and subtropical areas.
Clinical manifestations of DENV 
infection mainly include headache, fever, weakness, enlargement of lymph
 node, leukopenia and etc., and bleeding, shock, hepatic injury or even 
death in severe cases. In recent years, climate change, urbanization, 
quick development of tourism and other factors have provided more rapid 
and convenient conditions for transmitting and spreading of DF, leading 
to constant expansion of epidemic area of DF.

	
	
	
		
	
	
				
		
			
	
	
	
		

		Channel
	
	
	
	

			
	
	
	
		
	




FAM
Dengue Virus I




VIC(HEX)
Dengue Virus II




ROX
Dengue Virus III




CY5
Dengue Virus IV





	
	
	
		
	
	
				
		
			
	
	
	
		

		Technical Parameters
	
	
	
	

			
	
	
	
		
	



 



Storage
Liquid: ≤-18℃ in dark; lyophilization:≤30℃ in dark




Shelf-life
Liquid: 9 months; lyophilization:12 months




Specimen Type
Fresh Serum




Ct
≤38




CV
≤5.0％




LoD
500 Copies/mL




Specificity
Perform cross reaction tests of 
Japanese encephalitis virus, Forest encephalitis virus, severe fever 
with thrombocytopenia syndrome, Xinjiang hemorrhagic fever, hantaan 
virus, hepatitis C virus, influenza A virus, influenza B virus and etc. 
No cross reaction is detected




Applicable Instruments
It can match the mainstream fluorescent PCR instruments on the market.
SLAN-96P Real-Time PCR Systems
ABI 7500 Real-Time PCR Systems
ABI 7500 Fast Real-Time PCR Systems
QuantStudio®5 Real-Time PCR Systems
LightCycler®480 Real-Time PCR Systems
LineGene 9600 Plus Real-Time PCR Detection Systems
MA-6000 Real-Time Quantitative Thermal Cycler
BioRad CFX96 Real-Time PCR System
BioRad CFX Opus 96 Real-Time PCR System		





	
	
	
		
	
	
				
		
			
	
	
	
		

		Total PCR Solution
 	








































                        

                    

                    

                        

                            

                                

                                    
                                
Therapeutic AreaGeneric NameBrand NameGene(s)
AnesthesiologySuccinylcholineAnectine; QuelicinRYR1/CACNA1S, BCHE
DesfluraneSupraneRYR1/CACNA1S
EnfluraneEthraneRYR1/CACNA1S
HalothaneInternational use onlyRYR1/ CACNA1S
IsofluraneForane; TerrellRYR1/CACNA1S
MethoxyfluraneInternational use onlyRYR1/CACNA1S
SevofluraneUltaneRYR1/CACNA1S
Articaine and EpinephrineUltacan; Ultacan ForteG6PD
ChloroprocaineClorotekal; NesacaineG6PD
Lidocaine and TetracaineSyneraG6PD
MepivacaineCarbocaine; PolocaineG6PD
Oxymetazoline and TetracaineKovanazeG6PD
RopivacaineNaropinG6PD
Lidocaine and PrilocaineLidopril; Prikaan; Oraqix; AgonEazeG6PD
LidocaineXylocaine; Lidomark 1/5; Lidomark 2/5; P-Care X; Akten; Lidoderm; LMX 4; LMX 5; Topicaine; LubricaineG6PD
MivacuriumMivacronBCHE
CardiologyCarvedilolCoregCYP2D6
LabetalolNormodyne; TrandateCYP2D6
FlecainideTambocorCYP2D6
PropafenoneRythmol SRCYP2D6
WarfarinCoumadin; JantovenCYP2C9/VKORC1/CYP4F2
AcenocoumarolInternational use onlyCYP2C9
VKORC1
CYP4F2
PhenprocoumonInternational use onlyVKORC1
CYP4F2
IrbesartanAvaproCYP2C9
LosartanCozaarCYP2C9
SimvastatinZocorSLCO1B1/CYP2C9, APOE
RosuvastatinCrestor; Ezallor SprinkleSLCO1B1/CYP2C9/ABCG2, APOE
LovastatinAltoprev; MevacorSLCO1B1/CYP2C9, APOE
AtorvastatinSLCO1B1/CYP2C9, APOE
PravastatinPravacholSLCO1B1/CYP2C9, APOE
FluvastatinSLCO1B1/CYP2C9, APOE
PitavastatinLivalo; ZypitamagSLCO1B1/CYP2C9, APOE
AspirinEcotrin; Bayer; Asctiptin; DurlazaCYP2C9
PrasugrelEffientCYP2C19/CYP2C9/CYP3A5/CYP2B6
ClopidogrelPlavixCYP2C19
TicagrelorBrilintaCYP2C19
RivaroxabanXareltoF5
MetoprololLopressor; Toprol XLCYP2D6
NebivololBystolicCYP2D6
AcebutololInternational use onlyCYP2D6
BetaxololInternational use onlyCYP2D6
BisoprololInternational use onlyCYP2D6
TimololBetimolCYP2D6
PropranololInderal; Inderal LA; InnoPran XL; Propranolol HCl Intensol; Inderal XL; HemangeolCYP2D6
MavacamtenCamzyosCYP2C19
ProcainamideNAT2
HydralazineApresolineNAT2
DentalCevimelineEvoxacCYP2D6
DermatologyDoxepinSilenor; Zonalon; Sinequan; PrudoxinCYP2D6/CYP2C19
AbrocitinibCibinqoCYP2C19
TacrolimusAstagraf XL; Prograf; Protopic; Envarsus XRCYP3A5
FluorouracilAdrucil; Carac; Efudex; FluoroplexDPYD
EndocrinologyEliglustatCerdelgaCYP2D6
GlimepirideAmarylCYP2C9
NateglinideStarlixCYP2C9
GastroenterologyDexlansoprazoleDexilantCYP2C19
EsomeprazoleNexiumCYP2C19
LansoprazolePrevacid; Prevacid SoluTabCYP2C19
OmeprazolePrilosecCYP2C19
PantoprazoleProtonixCYP2C19
RabeprazoleAcipHexCYP2C19
MetoclopramideReglanCYP2D6
DronabinolSyndros; MarinolCYP2C9
OndansetronZofran; ZuplenzCYP2D6
TropisetronInternational use onlyCYP2D6
PalonosetronAloxiCYP2D6
MeclizineAntivert; Bonine; Dramamine Less Drowsy; Motion-Time; Travel Sickness; Travel-EasyCYP2D6
SulfasalazineAzulfidineNAT2/G6PD
MesalazineApriso; Asacol HD; Canasa; Delzicol; Lialda; Pentasa; Rowasa; SfRowasaG6PD
GynecologyDrospirenone and Ethinyl EstradiolJasmiel; Lo-Zumandimine; Loryna; Nikki; Ocella; Syeda; Vestura; Yasmin 28; YAZ; Zarah; ZumandimineCYP2C19
Hormonal Contraceptives For Systemic UseF5
ElagolixOrilissaSLCO1B1
FlibanserinAddyiCYP2C19
HematologyAvatrombopagDopteletF5/CYP2C9/F2
LusutrombopagMulpletaF5/F2
EltrombopagPromactaF5
Methylene BlueProvayBlue; Urolene BlueG6PD
ImmunologySiponimodMayzentCYP2C9
CevimelineEvoxacCYP2D6
TacrolimusAstagraf XL; Prograf; Protopic; Envarsus XRCYP3A5
SirolimusRapamuneCYP3A5
AzathioprineAzasan; ImuranTPMT/NUDT15
Infectious DiseasesVoriconazoleVfendCYP2C19
Quinine SulfateQualaquinCYP2D6
EfavirenzSustivaCYP2B6
NevirapineViramune; Viramune XRCYP2B6
AbacavirZiagenHLA-B
DolutegravirTivicayUGT1A1
RaltegravirIsentressUGT1A1
Atazanavir and RitonavirAvailable only as genericUGT1A1
AtazanavirReyatazUGT1A1
FlucloxacillinInternational use onlyHLA-B
AmikacinArikayceMT-RNR1
TobramycinTobrex; Bethkis; Kitabis Pak; Tobi; Tobi PodhalerMT-RNR1
GentamicinGentakMT-RNR1
KanamycinInternational use onlyMT-RNR1
ParomomycinHumatinMT-RNR1
PlazomicinZemdriMT-RNR1
StreptomycinInternational use onlyMT-RNR1
BoceprevirVictrelisIFNL3/IFNL4
TelaprevirIncivekIFNL3/IFNL4
SimeprevirOlysioIFNL3/IFNL4
Peginterferon Alfa-2APegasysIFNL3/IFNL4
Peginterferon Alfa-2BPegIntron; SylatronIFNL3/IFNL4
RibavirinIFNL3/IFNL4
IsoniazidNydrazidNAT2
Rifampin, Isoniazid, and PyrazinamideRifaterNAT2
EthambutolMyambutolNAT2
4-Aminosalicylic AcidPaserG6PD
CeftriaxoneRocephinG6PD
SulfadiazineSilvadeneG6PD
Sulfamethoxazole and TrimethoprimBactrim; Septra; SulfatrimNAT2/G6PD
SulfacetamideBleph-10; Klaron; Ovace; Sodium Sulfacetamide WashG6PD
SulfisoxazoleGantrisin Pediatric; TruxazoleG6PD
SulfadimidineAvailable only as genericG6PD
SulfamethoxazoleG6PD
NorfloxacinInternational use onlyG6PD
Nalidixic AcidNegGramG6PD
OfloxacinG6PD
FurazolidoneFuroxoneG6PD
NeurologyGalantamineRazadyne; Razadyne ERCYP2D6
DonepezilAriceptCYP2D6
PhenytoinDilantin; PhenytekCYP2C19/CYP2C9/HLA-B
FosphenytoinCerebyxCYP2C19/CYP2C9/HLA-B
CarbamazepineCarbatrol; Epitol; Equetro; Tegretol; Tegretol-XRHLA-B/HLA-A
OxcarbazepineOxtellar; TrileptalHLA-B
BrivaracetamBriviactCYP2C19
LacosamideVimpatCYP2C19
DeutetrabenazineAustedoCYP2D6
TetrabenazineXenazineCYP2D6
ValbenazineIngrezzaCYP2D6
Dextromethorphan and QuinidineNuedextaCYP2D6
SiponimodMayzentCYP2C9
RimegepantNurtecCYP2C9
DiazepamValium; Diastat AcuDial; Diazepam Intensol; Diastat PediatricCYP2C19
ClobazamOnfi; SympazanCYP2C19
MidazolamNayzilamCYP3A5
AmifampridineRuzurgiNAT2
Amifampridine PhosphateFirdapseNAT2
LecanemabLeqembiAPOE
AducanumabAduhelmAPOE
OncologyTamoxifenSoltamoxCYP2D6/F5/F2
ErdafitinibBalversaCYP2C9
GefitinibIressaCYP2D6
RucaparibRubracaCYP2D6
BelzutifanWeliregCYP2C19
TegafurInternational use onlyDPYD
CisplatinPlatinol-AQTPMT
BelinostatBeleodaqUGT1A1
IrinotecanCamptosar; OvivydeUGT1A1
Sacituzumab Govitecan-hziyTrodelvyUGT1A1
NilotinibTasignaUGT1A1
PazopanibVotrientUGT1A1/HLA-B*5701
BinimetinibMektoviUGT1A1
FluorouracilAdrucil; Carac; Efudex; FluoroplexDPYD
CapecitabineXelodaDPYD
MercaptopurinePurinethol; PurixanTPMT/NUDT15
Peginterferon Alfa-2BPegIntron; SylatronIFNL3/IFNL4
ThioguanineTabloidTPMT/NUDT15
FlutamideEulexinG6PD
TrametinibMekinistG6PD
DoxorubicinAdriamycin; DoxilG6PD
DabrafenibTafinlarG6PD
RasburicaseElitekG6PD
OphthalmologyTimololBetimolCYP2D6
Pain ManagementCelecoxibCelebrexCYP2C9
LumiracoxibInternational use onlyCYP2C9
AceclofenacInternational use onlyCYP2C9
FlurbiprofenAnsaidCYP2C9
PiroxicamFeldeneCYP2C9
MeloxicamAnjeso; Mobic; Qmiiz ODT; VivlodexCYP2C9
IbuprofenAddaprin;
 Advil Junior Strength; Advil Migraine; Advil; Caldolor; Childrens 
Advil; Childrens Motrin; Dyspel; Genpril; GoodSense Ibuprofen Childrens;
 GoodSense Ibuprofen; IBU; Ibuprofen Childrens; Infants Advil ; KS 
Ibuprofen; Motrin Childrens;
 Motrin IB; Motrin Infants Drops; NeoProfen; Provil		CYP2C9
LornoxicamInternational use onlyCYP2C9
TenoxicamInternational use onlyCYP2C9
DiclofenacDiclozor; Flector; Pennsaid; Voltaren; Xrylix; Cambia; Zipsor; ZorvolexCYP2C9
IndomethacinIndocin; TivorbexCYP2C9
NaproxenAleve; EC-Naprosyn; EC-Naproxen; GoodSense Naproxen Sodium; Mediproxen; Naprelan; Naprosyn; Naproxen DRCYP2C9
AspirinEcotrin; Bayer; Asctiptin; DurlazaCYP2C9
MetamizoleInternational use onlyCYP2C9, G6PD
TramadolUltram; ConZipCYP2D6/CYP2B6/COMT/OPRM1
MethadoneDolophine; Methadone HCL Intensol; Methadose; Diskets DispersibleCYP2D6/CYP2B6/COMT/OPRM1
OxycodoneOxaydo; OxyCONTIN; Roxicodone; Xtampza ERCYP2D6/COMT/OPRM1
HydrocodoneHysingla ER; Zohydro ERCYP2D6/COMT/OPRM1
CodeineAvailable only as genericCYP2D6/COMT/OPRM1
OliceridineOlinvykCYP2D6
LofexidineLucemyraCYP2D6
MorphineArymo ER; Duramorph; Infumorph 200; Infumorph 500; Kadian; Mitigo; MorphaBond ER; MS ContinCOMT/OPRM1
SufentanilDsuvia; SufentaCOMT/OPRM1
RemifentanilUltivaCOMT/OPRM1
AlfentanilAlfentaCOMT/OPRM1
HydromorphoneDilaudidCOMT/OPRM1
LevomethadoneInternational use onlyCOMT/OPRM1
FentanylAbstral; Actiq; Duragesic; Fentora; Ionsys; Lazanda; Sublimaze; SubsysCOMT/OPRM1
BuprenorphineBelbuca; Buprenex; Butrans; Probuphine Implant Kit; SublocadeCOMT/OPRM1
NaltrexoneVivitrolCOMT/OPRM1
PsychiatrySertralineZoloftCYP2C19/CYP2B6
FluoxetineProzac; SarafemCYP2D6
CitalopramCelexaCYP2C19/CYP2D6
EscitalopramLexaproCYP2C19/CYP2D6
FluvoxamineLuvox; Luvox CRCYP2D6
ParoxetinePaxil; Pexeva; BrisdelleCYP2D6
DuloxetineCymbalta; Drizalma SprinkleCYP2D6
VenlafaxineEffexorCYP2D6
NefazodoneSerzoneCYP2D6
MirtazapineRemeronCYP2D6
VortioxetineTrintellixCYP2D6
BupropionAplenzin; Forfivo XL; Wellbutrin SR; Wellbutrin XLCYP2B6
AripiprazoleAbilifyCYP2D6
Aripiprazole LauroxilAristada; Aristada InitioCYP2D6
BrexpiprazoleRexultiCYP2D6
CariprazineVraylarCYP2D6
HaloperidolHaldolCYP2D6
RisperidoneRisperdalCYP2D6
PaliperidoneInvegaCYP2D6
IloperidoneFanaptCYP2D6
ClozapineClozaril; VersaclozCYP2D6
ZuclopenthixolInternational use onlyCYP2D6
PerphenazineTrilafonCYP2D6
ThioridazineMellarilCYP2D6
PimozideOrapCYP2D6
DoxepinSilenor; Zonalon; Sinequan; PrudoxinCYP2D6/CYP2C19
AtomoxetineStratteraCYP2D6
ViloxazineQelbreeCYP2D6/SLCO1B1
AmphetamineDyanavel XR; Adzenys XR-ODT; Adzenys ERCYP2D6
ModafinilProvigilCYP2D6
PitolisantWakixCYP2D6
ClomipramineAnafranilCYP2D6/CYP2C19
ImipramineTofranilCYP2D6/CYP2C19
TrimipramineSurmontilCYP2D6/CYP2C19
AmitriptylineElavil; VanatripCYP2D6/CYP2C19
AmoxapineAsendinCYP2D6
DesipramineNorpraminCYP2D6
ProtriptylineVivactilCYP2D6
NortriptylinePamelorCYP2D6
DiazepamValium; Diastat AcuDial; Diazepam Intensol; Diastat PediatricCYP2C19
RespiratoryUmeclidiniumIncruse ElliptaCYP2D6
ArformoterolBrovanaCYP2D6/UGT1A1
IndacaterolArcapta NeohalerUGT1A1
DextromethorphanRobitussin; Delsym; Pediacare; RobafenCYP2D6
IvacaftorKalydecoCFTR
Ivacaftor, Tezacaftor, and ElexacaftorTrikaftaCFTR
Ivacaftor and LumacaftorOrkambiCFTR
Ivacaftor and TezacaftorSymdekoCFTR
RheumatologyLesinuradZurampicCYP2C9
AllopurinolZyloprimHLA-B
UpadacitinibRinvoqCYP2D6
AzathioprineAzasan; ImuranTPMT/NUDT15
CelecoxibCelebrexCYP2C9
LumiracoxibInternational use onlyCYP2C9
AceclofenacInternational use onlyCYP2C9
FlurbiprofenAnsaidCYP2C9
PiroxicamFeldeneCYP2C9
MeloxicamAnjeso; Mobic; Qmiiz ODT; VivlodexCYP2C9
IbuprofenAddaprin;
 Advil Junior Strength; Advil Migraine; Advil; Caldolor; Childrens 
Advil; Childrens Motrin; Dyspel; Genpril; GoodSense Ibuprofen Childrens;
 GoodSense Ibuprofen; IBU; Ibuprofen Childrens; Infants Advil ; KS 
Ibuprofen; Motrin Childrens;
 Motrin IB; Motrin Infants Drops; NeoProfen; Provil		CYP2C9
LornoxicamInternational use onlyCYP2C9
TenoxicamInternational use onlyCYP2C9
DiclofenacDiclozor; Flector; Pennsaid; Voltaren; Xrylix; Cambia; Zipsor; ZorvolexCYP2C9
IndomethacinIndocin; TivorbexCYP2C9
NaproxenAleve; EC-Naprosyn; EC-Naproxen; GoodSense Naproxen Sodium; Mediproxen; Naprelan; Naprosyn; Naproxen DRCYP2C9
NabumetoneRelafen DSCYP2C9
AspirinEcotrin; Bayer; Asctiptin; DurlazaCYP2C9
CarisoprodolSoma; VanadomCYP2C19
SulfasalazineAzulfidineNAT2/G6PD
PegloticaseKrystexxaG6PD
ProbenecidBenemid; ProbalanG6PD
Smoking CessationBupropionAplenzin; Forfivo XL; Wellbutrin SR; Wellbutrin XLCYP2B6
UrologyTamsulosinFlomaxCYP2D6
TolterodineDetrolCYP2D6
FesoterodineToviazCYP2D6
DarifenacinEnablexCYP2D6
MirabegronMyrbetriqCYP2D6
PhenazopyridineAZO Urinary Pain Relief; Pyridium; Urinary Pain ReliefG6PD
ToxicologySodium NitriteNithiodoteG6PD
SuccimerChemetG6PD
DimercaprolBal In OilG6PD
SupplementsVitamin CAcerola C 500; Ascor; BProtected Vitamin C; Fruit C 500; Fruity C [OTC]; Vita-C; VitaChew Vit C Citrus BurstG6PD
Vitamin KMephylonG6PD
Infectious Diseases/OphthalmologyMoxifloxacinAvelox; Moxeza; VigamoxG6PD